Recurrent ventricular tachycardia.

Ventricular tachycardia is a dangerous form of arrhythmia, and is usually a manifestation of serious heart disease, either acute ischaemia, severe heart failure, myocarditis, or sometimes drug intoxication , especially digitalis. Treatment is only rarely based on aetiology. The most effective therapy has been found to be electrical conversion (Lown et al. therefore it is often compulsory to repeat cardio-versions and to use antiarrhythmic agents to retain sinus rhythm. The purpose of the present paper is to report a case of recurrent ventricular tachy-cardia, and to show that the key problem is how to prevent new attacks after successful electrical conversion. years earlier he had had a myocardial infarction, but he recovered and was able to resume work. He was admitted to our hospital for ventricular tachycardia of three days' duration despite treatment with quinidine and pro-cainamide. On admission he was in a poor condition, being cyanotic, hypotensive, and in heart failure. The electrocardiogram revealed ventricular tachycardia, with a rate of 180. He was given quinidine sulphate (2-4 g. a day) and four doses of procainamide, 1000 mg. each, intramuscularly or intravenously. Since tachycardia persisted for 10 days after admission, a non-synchronized direct current countershock was given. This was the first defibrillation in our hospital. A single 100 watt-second shock converted the heart to sinus rhythm. The electrocardiogram revealed sinus rhythm, the characteristics of inferior wall infarction, and ischaemic anterior wall lesions. After defibrillation he was given digoxin 0-25 mg. twice daily, quinidine bisulphate 0 4 gr. twice daily, and prednisolone 5 mg. twice daily. Twelve days after defibrillation he had the first relapse (Fig.). Intravenous procainamide and carotid sinus massage failed, but the first shock (100 watt-seconds) again restored sinus rhythm. During the following five days there were two relapses, both converted to sinus rhythm by defibrillation. There were nine more attacks of ventricular tachy-cardia during the next 11 months, and each one was converted to sinius rhythm by a single 100 watt-second D-C shock. During the next year the patient had one attack in January and another in November. The following year the first relapse occurred in January. Apart from a few weeks in the summer, the patient was then permanently in hospital because of recurring attacks of ventricular tachycardia and poor condition. He died at the end of October 1966. In all, this patient was defibrillated for 47 attacks of ventricular tachycardia. The first shock of 100 …